Study on the Effects of Biologically Active Amino Acids on the Micellization of Anionic Surfactant Sodium Dodecyl Sulfate (SDS) at Different Temperatures

The micellar properties of the anionic surfactant, sodium dodecyl sulfate (SDS) are modified by biologically active amino acids. Amino acids (AAs) have experienced a variety interactions and proposed to influence SDS micelles due their nominated hydrophobic interactions. present study determines critical concentration (CMC) in aqueous solutions as well solutions. Three (glutamic acid, histidine, tryptophan) considered here. conductometric measurements were carried out using wide range concentrations at different temperatures. Surface tension experiments also been applied estimate many surface parameters including excess (?max), occupied area per surfactant molecule (Amin), CMC (?cmc), pressure (?cmc) Gibbs free energy adsorption (?Gads°), enthalpy ?Hm° packing parameter (CPP). Interestingly, values water estimated method comparable with corresponding obtained conductance method. thermodynamic micellization evaluated both presence absence AAs. additives AAs work reduce values, parameters. This reduction is highly dependent on hydrophobicity AA side chain. Negative ?Gm°, elucidate that thermodynamically spontaneous exothermic. outcomes here might be utilized for pharmaceutical applications stabilize proteins inhibit protein aggregation.